Two morphological variants of biofilms were identified in our isolates, with 48.6% of the isolates showing mainly yeast and pseudohyphae-like structures, while the remaining ones were predominantly filamentous forms. Candida parapsilosis was the largest producer, followed by Candida tropicalis and C. The anti-biofilm effect of AbA on Candida albicans was examined using field emission scanning electron microscope (FESEM) analysis.Results:A total of 35 (29.7%) of 118 Candida isolates were regarded as biofilm producers in this study. The determination of AbA planktonic and biofilm MICs was performed based on a micro-broth dilution method. Aureobasidin A (AbA), a cyclic depsipeptide targeting fungal sphingolipid biosynthesis, has been shown to be effective against several Candida species.Aims:The aim of this study was to investigate Candida biofilm growth morphology, its biomass, metabolic activity, and to determine the effects of AbA on the biofilm growth.Methods:The biofilm forming ability of several clinical isolates of different Candida species from our culture collection was determined using established methods (crystal violet and XTT assays). Background:Biofilm is known to contribute to the antifungal resistance of Candida yeasts.
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